Plant Transcription Factor Database
Previous version: v3.0
Tarenaya hassleriana
BBR-BPC Family
Species TF ID Description
XP_010518926.1BBR-BPC family protein
XP_010526572.1BBR-BPC family protein
XP_010526573.1BBR-BPC family protein
XP_010527829.1BBR-BPC family protein
XP_010527830.1BBR-BPC family protein
XP_010530298.1BBR-BPC family protein
XP_010530299.1BBR-BPC family protein
XP_010530300.1BBR-BPC family protein
XP_010530301.1BBR-BPC family protein
XP_010530302.1BBR-BPC family protein
XP_010530303.1BBR-BPC family protein
XP_010530304.1BBR-BPC family protein
XP_010530305.1BBR-BPC family protein
XP_010530309.1BBR-BPC family protein
XP_010530310.1BBR-BPC family protein
XP_010530311.1BBR-BPC family protein
XP_010530312.1BBR-BPC family protein
XP_010530313.1BBR-BPC family protein
XP_010530315.1BBR-BPC family protein
XP_010530316.1BBR-BPC family protein
XP_010531487.1BBR-BPC family protein
XP_010531488.1BBR-BPC family protein
XP_010538354.1BBR-BPC family protein
XP_010539043.1BBR-BPC family protein
XP_010539044.1BBR-BPC family protein
XP_010539045.1BBR-BPC family protein
XP_010554354.1BBR-BPC family protein
XP_010554362.1BBR-BPC family protein
XP_010554370.1BBR-BPC family protein
XP_010554371.1BBR-BPC family protein
XP_010555253.1BBR-BPC family protein
XP_010555254.1BBR-BPC family protein
BBR/BPC Family Introduction

We identified BASIC PENTACYSTEINE1 (BPC1) as a regulator of the homeotic Arabidopsis thaliana gene SEEDSTICK (STK), which controls ovule identity, and characterized its mechanism of action. A combination of tethered particle motion analysis and electromobility shift assays revealed that BPC1 is able to induce conformational changes by cooperative binding to purine-rich elements present in the STK regulatory sequence. Analysis of STK expression in the bpc1 mutant showed that STK is upregulated. Our results give insight into the regulation of gene expression in plants and provide the basis for further studies to understand the mechanisms that control ovule identity in Arabidopsis.

Kooiker M, Airoldi CA, Losa A, Manzotti PS, Finzi L, Kater MM, Colombo L.
BASIC PENTACYSTEINE1, a GA binding protein that induces conformational changes in the regulatory region of the homeotic Arabidopsis gene SEEDSTICK.
Plant Cell. 2005 Mar;17(3):722-9. Epub 2005 Feb 18.
PMID: 15722463

BBR is nuclear targeted and is a characterized nuclear localization signal (NLS) sequence, a DNA-binding domain extended up to 90 aa at the C-terminus and a putative N-terminal activation domain. The corresponding gene has no introns and is ubiquitously expressed in barley tissues. In co-transfection experiments, BBR activates (GA/TC)8-containing promoters, and its overexpression in tobacco leads to a pronounced leaf shape modification. BBR has properties of a GAGA-binding factor, but the corresponding gene has no sequence homology to Trl and Psq of Drosophila, which encode functionally analogous proteins. In Arabidopsis, (GA/TC)8 repeats occur particularly within 1500 bp upstream of gene start codons included in some homeodomain genes of different classes. The data presented suggest that expression of the barley BKn3 is regulated, at least in part, by the binding of the transcription factor BBR to GA/TC repeats.

Santi L, Wang Y, Stile MR, Berendzen K, Wanke D, Roig C, Pozzi C, Muller K, Muller J, Rohde W, Salamini F.
The GA octodinucleotide repeat binding factor BBR participates in the transcriptional regulation of the homeobox gene Bkn3.
Plant J, 2003. 34(6): p. 813-26.
PMID: 12795702